Preliminary Data on the Feasibility of Bone Marrow Screening on the Sysmex XE-2100 Automated Hematology Analyzer

نویسندگان

  • W. GOOSSENS
  • C. BRUSSELMANS
  • N. BOECKX
چکیده

In the present study we investigated the potential of the Sysmex XE-2100 automated hematology analyzer as a screening device for bone marrow (BM) aspirates. We evaluated BM cellularity, white blood cell (WBC) differential count, immature granulocyte (IG) count, nucleated red blood cell (NRBC) count, granulocyte/erythroid (G/E) and myeloid/erythroid (M/E) ratio, and potential pathologyrelated scattergrams (‘pathology patterns’). Our data are derived from analyses of 160 BM samples of patients with hematological malignancies. Our preliminary data indicate that the Sysmex XE-2100 opens new perspectives for use as a primary screening device for BM samples, particularly in cases of acute and chronic lymphocytic and myeloid leukemias, where distinct pathology-related scattergram patterns have the potential to be of diagnostic help. Software improvements are required for further progress.

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تاریخ انتشار 2002