Preliminary Data on the Feasibility of Bone Marrow Screening on the Sysmex XE-2100 Automated Hematology Analyzer
نویسندگان
چکیده
In the present study we investigated the potential of the Sysmex XE-2100 automated hematology analyzer as a screening device for bone marrow (BM) aspirates. We evaluated BM cellularity, white blood cell (WBC) differential count, immature granulocyte (IG) count, nucleated red blood cell (NRBC) count, granulocyte/erythroid (G/E) and myeloid/erythroid (M/E) ratio, and potential pathologyrelated scattergrams (‘pathology patterns’). Our data are derived from analyses of 160 BM samples of patients with hematological malignancies. Our preliminary data indicate that the Sysmex XE-2100 opens new perspectives for use as a primary screening device for BM samples, particularly in cases of acute and chronic lymphocytic and myeloid leukemias, where distinct pathology-related scattergram patterns have the potential to be of diagnostic help. Software improvements are required for further progress.
منابع مشابه
Automation of bone marrow aspirate examination using the XE-2100 automated hematology analyzer.
BACKGROUND Attempts to analyze bone marrow aspirates have been reported with the use of several automated blood cell counters, but sufficient accuracy in examination is not acquired yet. Major problems have included difficulties in correctly differentiating various immature cells and interference by lipid in bone marrow aspirates. The goal of this study was to solve these problems to attain mor...
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